What's The Story With Propanediol?

Written By DONNA FLAGG - March 16 2019


Donna Flagg
August 03 2019

@Katherine – yes, they do call it antifreeze, but non-toxic antifreeze. An important distinction, though I’m not I’m convinced it’s been proven safe in a way that could allay fears of what effects it could have on the body. Thanks for the correction. It is reflected in the blog.

Donna Flagg @
August 03 2019

@Jim – thank you! I really appreciate the guidance. I read it wrong. I adjusted the blog.

August 03 2019

2,2-bis(bromomethyl)-1,3-propanediol is not the same thing as 1,3-propanediol, as is shown in the chemical name. And to say that 1,3-propanediol is “synonymous” with ethylene glycol is forgetting that these aren’t just words, but three dimensional molecules. They exist in different three-dimensional shapes. This means they behave differently. So if you were to ingest antifreeze, your body would be poisoned. But 1,3-propanediol doesn’t look the same to the 3D enzymes in your body. So it’s not poisonous.

Having said that, as with any newly created substance, we still need to do more research to make sure it’s safe. But citing research that refers to an entirely different chemical and highlighting part of the name that matches the subject of your article is misleading.

Katherine Gray
August 03 2019

I appreciate that you ask the question re: substances and products derived from corn, yet as you say-is the corn genetically modified? And, what was used as a pesticide on that corn?
I wish that these dangerous pesticides would be banned – period.

I also wanted to point out that anti-freeze isn’t made with propylene glycol, it’s made with

ethylene glycol. *

Fred Lander
April 28 2019

I am looking for a toothpaste or mouthwash with pomegranate seed oil and found one that looks promising, but with the propanediol.
I did find a peer reviewed toxicology study on the vapor that looks a little bit optimistic. The cancer results you posted are more convincing to me, so far.

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